Gene Segments&Fragments

Synthetic Gene Fragments are an inexpensive, rapid, and efficient way to build the genes you need for your research. Gene Fragments from Betazymes will improve your cloning process by minimizing colony screening and by that saving the time and money by dramatically reducing cloning and sequencing costs.

Betazymes' DNA synthesis technology outperforms the competition with exceptionally low error rates. In a direct comparison of Gene Fragment products, our results consistently showed the lowest error rate. The graph to the left represents the average error rate for Gene sequences ordered from us. The results show that our gene fragments have greater sequence accuracy over eBlocks and gBlocks with an average of 2-fold greater accuracy in sequence fidelity for Gene Fragments over gBlocks.

At Betazymes, the precise manipulation of gene fragments is a cornerstone of our agile and innovative approach to enzyme engineering. We routinely work with smaller, synthesized or amplified DNA fragments, treating them as modular building blocks to construct larger genes and genetic circuits. Our expertise lies in the accurate and efficient assembly of these gene fragments using a variety of cutting-edge techniques, including seamless cloning methods and ligation-independent cloning. This allows us to rapidly create a diverse array of genetic constructs, incorporating specific mutations, domain shuffles, and regulatory elements with exceptional control and fidelity.

Our ability to manipulate gene fragments provides us with significant flexibility in tailoring enzyme properties and optimizing gene expression. By precisely joining these fragments, we can engineer enzymes with enhanced activity, stability, or substrate specificity. Furthermore, we can construct complex expression vectors by assembling gene fragments alongside promoters, terminators, and selection markers, ensuring optimal protein production in chosen host organisms. This modular approach to working with gene fragments accelerates our research cycles and allows us to rapidly iterate through different enzyme designs and expression strategies.

The skilled manipulation of gene fragments is integral to our R&D pipeline at Betazymes. It empowers our scientists to rapidly prototype and test a wide range of enzyme variants and genetic constructs. This agile approach, driven by our proficiency in handling and assembling gene fragments, allows us to quickly adapt to new research findings and customer needs. By treating DNA as a highly manipulable set of building blocks, we can efficiently generate novel biocatalysts and deliver customized enzyme solutions with speed and precision.